Peptide Research: Selank – Studies, Research Use, and Scientific Background

What is Selank?

Selank is a synthetic peptide developed as an analogue of the naturally occurring tetrapeptide tuftsin. It is widely researched in laboratory settings for its potential effects on neuroprotection, cognitive function, stress resilience, and modulation of the immune system in preclinical models.
For laboratory research use only. Not for human or veterinary use.

Key Scientific Studies

• Anxiolytic and Cognitive Effects: A 2016 study in Behavioural Brain Research demonstrated Selank’s anxiolytic and cognitive-enhancing properties in rodent models, suggesting modulation of the GABAergic and monoaminergic systems.
  Andreeva et al., 2016
• Immunomodulation: Laboratory research has shown that Selank may modulate cytokine production and immune responses in animal and in vitro studies.
  Ershov et al., 2009

Laboratory Research Applications

• Investigation of anxiety, stress, and depression in preclinical models
• Research on cognitive function and memory
• Immunomodulation and cytokine signaling studies
• Study of neuroprotective pathways

Mechanism of Action (in Research Context)

Selank is believed to exert its effects by influencing GABAergic, serotonergic, and dopaminergic neurotransmitter systems, as well as by modulating immune cytokines. Laboratory studies support its role in neuroprotection, anxiolytic activity, and cognitive enhancement.

Reference Dosing Schedules from Published Studies

The following dosing protocols have been reported in published laboratory and preclinical studies of Selank:

• Common Dose Range (animal studies): 250–500 mcg/kg, administered intranasally or intraperitoneally
• Duration: Typically 7–14 days, depending on experimental protocol