Peptide Research: Oxytocin – Studies, Research Use, and Scientific Background

What is Oxytocin?

Oxytocin is a naturally occurring nonapeptide hormone and neuropeptide produced in the hypothalamus and secreted by the posterior pituitary gland. In laboratory research, oxytocin is studied for its roles in social behavior, bonding, stress modulation, and a variety of physiological processes in preclinical models.
For laboratory research use only. Not for human or veterinary use.

Key Scientific Studies

• Social Behavior and Bonding: Research published in Science (2005) demonstrated that oxytocin administration facilitated social recognition and bonding behaviors in animal models.
  Ferguson et al., 2005
• Stress and Anxiety Modulation: Laboratory studies have shown oxytocin’s involvement in the regulation of stress responses and anxiety in preclinical models, with evidence for its influence on the hypothalamic-pituitary-adrenal axis.
  Neumann & Landgraf, 2012

Laboratory Research Applications

• Studies on social behavior, bonding, and maternal responses
• Research on anxiety, stress modulation, and emotional regulation
• Preclinical models of addiction, reward, and social cognition
• Investigation of physiological roles in reproduction and lactation

Mechanism of Action (in Research Context)

Oxytocin exerts its effects by binding to oxytocin receptors (OXTR) found in the brain and throughout the body. In laboratory research, it is recognized for its modulation of neuronal signaling, social cognition, and influence on neuroendocrine and emotional pathways in preclinical models.

Reference Dosing Schedules from Published Studies

The following dosing protocols have been reported in published laboratory and preclinical studies of oxytocin:

• Common Dose Range (animal studies): 0.1–1 mg/kg, typically administered intraperitoneally or subcutaneously
• Duration: Varies by protocol; often ranges from single dose to 7–14 days in preclinical studies