Peptide Research: GHRP-2 – Studies, Research Use, and Scientific Background

What is GHRP-2?

Growth Hormone Releasing Peptide-2 (GHRP-2) is a synthetic hexapeptide and potent agonist of the ghrelin/growth hormone secretagogue receptor. GHRP-2 is studied extensively in laboratory research for its effects on growth hormone release, appetite stimulation, and metabolic function in preclinical models.
For laboratory research use only. Not for human or veterinary use.

Key Scientific Studies

• Growth Hormone Secretion: Laboratory studies published in Endocrinology have shown that GHRP-2 robustly increases growth hormone release in animal models and in vitro pituitary assays.
  Bowers et al., 1991
• Appetite and Metabolic Effects: Preclinical research has demonstrated that GHRP-2 stimulates appetite, food intake, and influences metabolic pathways in rodent models.
  Nakazato et al., 2003

Laboratory Research Applications

• Investigation of growth hormone regulation and release
• Research on appetite and energy homeostasis
• Preclinical models of metabolic and endocrine disorders
• Studies of ghrelin receptor activation

Mechanism of Action (in Research Context)

GHRP-2 binds to the growth hormone secretagogue receptor (GHS-R1a), stimulating the pituitary gland to release growth hormone. It also activates the ghrelin pathway, which plays a role in appetite regulation and energy metabolism in laboratory models.

Reference Dosing Schedules from Published Studies

The following dosing protocols have been reported in published laboratory and preclinical studies of GHRP-2:

• Common Dose Range (animal studies): 100–300 mcg/kg, administered intraperitoneally or subcutaneously
• Duration: Varies by protocol; most studies utilize 7–21 day periods